| Model group | Models | Authors | Contributed by | Type | Cite as | License | Tags |
|---|---|---|---|---|---|---|---|
| Model group | Models | Authors | Contributed by | Type | Cite as | License | Tags |
| APARENT | 2 | Nicholas Bogard et al. | Shabnam Sadegharmaki et al. | None | https://doi.org/10.1101/300061 | MIT | |
| AttentiveChrome | 55 | Ritambhara Singh et al. | Jack Lanchantin et al. | pytorch | https://doi.org:/10.1101/329334 | MIT | RNA expression |
| BPNet-OSKN | 1 | Ziga Avsec | Ziga Avsec | None | https://doi.org/10.1101/737981 | MIT | DNA binding |
| BPNet_Dmel_OreR_2to3hr_ZDTBCG | 1 | Melanie Weilert and Kaelan Brennan | Melanie Weilert and Kaelan Brennan | None | https://doi.org/10.1101/2022.12.20.520743 | MIT | |
| Basenji | 1 | David R. Kelley | Ziga Avsec | tensorflow | https://doi.org/10.1101/gr.227819.117 | Apache License v2 | RNA expression, Histone modification, DNA accessibility |
| Basset | 1 | David R. Kelley | Roman Kreuzhuber | pytorch | https://doi.org/10.1101/gr.200535.115 | MIT | DNA accessibility |
| CleTimer | 2 | Leohnard Wachutka et al. | Leohnard Wachutka et al. | None | Apache License v2 | RNA splicing | |
| CpGenie | 51 | Haoyang Zeng | Roman Kreuzhuber | custom, keras | https://doi.org/10.1093/nar/gkx177 | Apache License v2 | DNA methylation |
| DeepBind | 927 | Babak Alipanahi et al. | Johnny Israeli | keras | https://doi.org/10.1038/nbt.3300 | BSD 3-Clause | DNA binding |
| DeepCpG_DNA | 5 | Christof Angermueller | Roman Kreuzhuber | keras |
https://doi.org/10.1186/s13059-017-1189-z
https://doi.org/10.5281/zenodo.1094823 |
MIT | DNA methylation |
| DeepFlyBrain | 1 | Ibrahim Ihsan Taskiran et al. | Ibrahim Ihsan Taskiran et al. | None | TBA | MIT | |
| DeepLiver | 3 | Carmen Bravo et al. | Carmen Bravo et al. | None |
Bravo
González-Blas Carmen. (2022). Enhancer grammar of liver cell types and hepatocyte zonation states. https://doi.org/10.1101/2022.12.08.519575 |
Other / Non-commercial (see LICENSE.txt) | |
| DeepMEL | 3 | Ibrahim Ihsan Taskiran et al. | Ibrahim Ihsan Taskiran et al. | None |
https://doi.org/10.1101/gr.260844.120
https://doi.org/10.1101/2019.12.21.885806 |
MIT | |
| DeepSEA | 3 | Jian Zhou et al. | Roman Kreuzhuber | None, pytorch |
https://doi.org/10.1038/s41588-018-0160-6
https://doi.org/10.1038/nmeth.3547 |
Non-comercial, CC-BY 3.0 | Histone modification, DNA binding, DNA accessibility |
| DeepSTARR | 1 | Bernardo P. de Almeida | Bernardo P. de Almeida | None | https://doi.org/10.1101/2021.10.05.463203 | MIT | |
| Divergent421 | 1 | Nancy Xu | Nancy Xu | None | MIT | DNA accessibility | |
| FactorNet | 30 | Daniel Quang et al. | Ziga Avsec | keras | https://doi.org/10.1101/151274 | MIT | DNA binding |
| Framepool | 1 | Alexander Karollus | Alexander Karollus | None | MIT | Translation | |
| HAL | 1 | Alexander B. Rosenberg | Jun Cheng et al. | None | https://doi.org/10.1016/j.cell.2015.09.054 | MIT | RNA splicing |
| KipoiSplice | 2 | Ziga Avsec et al. | Ziga Avsec et al. | sklearn | https://doi.org/10.1101/375345 | MIT | RNA splicing |
| MMSplice | 5 | Jun Cheng | Jun Cheng | custom | MIT | RNA splicing | |
| MPRA-DragoNN | 2 | Rajiv Movva, Surag Nair | Rajiv Movva, Surag Nair | None | https://doi.org/10.1101/393926 | MIT | RNA expression |
| MaxEntScan | 2 | Gene Yeo et al. | Jun Cheng et al. | None | https://doi.org/10.1089/1066527041410418 | MIT | RNA splicing |
| OptMRL | 1 | Frederick Korbel, Ekaterina Eroshok, Uwe Ohler | Frederick Korbel, Ekaterina Eroshok, Uwe Ohler | None | https://doi.org/10.1101/2023.06.02.543405 | GPL-3 | |
| Optimus_5Prime | 1 | Paul J. Sample | Ban Wang | None | https://doi.org/10.1101/310375 | MIT | Translation |
| SeqVec | 3 | Michael Heinzinger, Ahmed Elnaggar et al. | Michael Heinzinger, Ahmed Elnaggar et al. | None |
https://doi.org/10.1101/614313
https://doi.org:/10.1101/614313 |
MIT | Protein properties, Protein structure |
| SiSp | 1 | Lara Urban | Lara Urban | keras | https://doi.org/10.1101/328138 | MIT | RNA splicing |
| TREDNet | 4 | Sanjarbek Hudaiberdiev | Sanjarbek Hudaiberdiev | None | https://medrxiv.org/cgi/content/short/2022.05.13.22275035v1 | CC-BY-ND | |
| Xpresso | 5 | Vikram Agarwal | Vikram Agarwal | None | https://doi.org/10.1016/j.celrep.2020.107663 | MIT | |
| a2z-chromatin | 2 | Travis Wrightsman | Travis Wrightsman | None | https://doi.org/10.1101/2021.11.11.468292 | MIT | DNA accessibility, DNA methylation, Plants |
| deepTarget | 1 | Byunghan Lee et al. | Ziga Avsec | None | https://arxiv.org/pdf/1603.09123.pdf | GPL-v3 | RNA binding |
| epidermal_basset | 60 | Daniel Kim | Daniel Kim | None | https://doi.org:/... | MIT | |
| extended_coda | 1 | Pang Wei Koh et al. | Johnny Israeli | keras | https://doi.org/10.1093/bioinformatics/btx243 | MIT | Histone modification |
| labranchor | 1 | Joseph M. Paggi et al. | Jun Cheng | keras | https://doi.org/10.1101/185868 | CC BY-NC 4.0 | RNA splicing |
| lsgkm-SVM | 322 | Dongwon Lee | Roman Kreuzhuber | None | https://doi.org/10.1093/bioinformatics/btw142 | MIT | DNA binding |
| pwm_HOCOMOCO | 600 | Ivan V. Kulakovskiy | Ziga Avsec | keras | https://doi.org/10.1093/nar/gkv1249 | MIT | DNA binding |
| rbp_eclip | 102 | Ziga Avsec | Ziga Avsec | keras | https://doi.org/10.1093/bioinformatics/btx727 | MIT | RNA binding |
| scbasset | 1 | Han Yuan, David R. Kelley | Han Yuan | keras | https://doi.org/10.1101/gr.200535.115 | Apache License 2.0 | scATAC accessibility |
Kipoi models
This repository hosts predictive models for genomics and serves as a model source for Kipoi. Each folder containing model.yaml is considered to be a single model.
Contributing models
-
Install kipoi:
pip install kipoi -
Run
kipoi ls. This will checkout thekipoi/modelsrepo to~/.kipoi/models) -
Follow the instructions on contributing/Getting started.
Using models (to predict, score variants, build new models)
To explore available models, visit http://kipoi.org/models. See kipoi/README.md and docs/using getting started for more information on how to programatically access the models from this repository using CLI, python or R.
Configuring local storage location
This model source (https://github.com/kipoi/models) is included in the Kipoi config file (~/.kipoi/config.yaml) by default:
# ~/.kipoi/config.yaml
model_sources:
kipoi:
type: git-lfs
remote_url: [email protected]:kipoi/models.git
local_path: ~/.kipoi/models/
auto_update: True
If you wish to keep the models stored elsewhere, edit the local_path accordingly.